When an explosion threatens a major metropolis, fire fighter Jack Thomas and his squad battle to save as many people as possible before the firestorm spreads. Meanwhile, Dr Jennifer Lewis and her short-staffed ER team desperately attempt to handle the horrific flood of burn victims. But both Jack and Jennifer are running out of time. Jennifer discovers two awful facts - that the fire was deliberately started and that the hospital is the next target. As the roaring flames encircle the ER, Jack and his men fight a last-ditch battle to save lives and reveal the truth.